Take home naloxone and the prevention of deaths from opiate overdose: two pilot schemes.
نویسندگان
چکیده
This project was funded by the Chief Scientist Office of the Scottish Executive; the executive accepts no responsibility for the information provided or the views expressed. Contributors: JSB analysed the data and conducted the preliminary interpretation of the results; she was responsible for drafting and revising the paper. DMC, WJG, MHH, GCP, and MR designed the study, secured the funding for the project, and advised throughout on the conduct and interpretation of the analysis. WJG identified the need for the study. All authors helped revise the paper and will act as guarantors. Competing interests: None declared.
منابع مشابه
Opiate users' knowledge about overdose prevention and naloxone in New York City: a focus group study
BACKGROUND Drug-induced and drug-related deaths have been increasing for the past decade throughout the US. In NYC, drug overdose accounts for nearly 900 deaths per year, a figure that exceeds the number of deaths each year from homicide. Naloxone, a highly effective opiate antagonist, has for decades been used by doctors and paramedics during emergency resuscitation after an opiate overdose. F...
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BACKGROUND AND AIMS Fatal outcome of opioid overdose, once detected, is preventable through timely administration of the antidote naloxone. Take-home naloxone provision directly to opioid users for emergency use has been implemented recently in more than 15 countries worldwide, albeit mainly as pilot schemes and without formal evaluation. This systematic review assesses the effectiveness of tak...
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Aims: Scotland was the first country to adopt take-home naloxone (THN) as a funded public health policy. We summarise the background and rigorous set-up for before/after monitoring to assess the impact on high-risk opiate-fatalities. Methods: Evidence-synthesis of prospectively monitored small-scale THN schemes led to a performance indicator for distribution of THN-kits relative to opiate-relat...
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INTRODUCTION Naloxone, an opiate antagonist that can avert opiate overdose morality, has long been prescribed to drug users in Europe and in a few US cities. However, there has been little documented evidence of naloxone distribution programs and their feasibility in the peer reviewed literature in the US. METHODS A pilot overdose prevention and reversal program was implemented in a New York ...
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The mortality and morbidity from heroin overdose have increased in the United States and internationally in the last decade. The lipid solubility allows the rapid deposition of heroin and its metabolites into the central nervous system and accounts for the "rush" experienced by users and for the toxicity. Risk factors for fatal and nonfatal heroin overdoses such as recent abstinence, decreased ...
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ورودعنوان ژورنال:
- BMJ
دوره 322 7291 شماره
صفحات -
تاریخ انتشار 2001